For me it depends on my comment. Most of the time I don't look for a response. There are exceptions though.

thanks dude. ambiguous, but at least it's an answer.

I don't really care about being acknowledged when I leave a comment.

But for me, on my blog, I have been trying to make an effort to acknowledge new visitors who are finding my site through the traffic sites. You know what it's like when you surf along for credits. Lame blog, click, lame blog, click, lame blog, cl-wait! that was a good one! dammit, where'd it go???

So if one of those folks likes my blog enough to leave a comment, I want to either respond to it at my blog and thank them for their visit or go to their blog and leave a commment, or better yet, both.

But I'm a more considerate person than you are. :P :D ;)

I got your reply in my mailbox this morning to my comment, and I thought that was very cool. But I know we all don't always get time to do that. I try to post a comment to my comments to get every one at once.

I don't expect a comment back. If you comment on my comment that's cool and if you don't that's cool too.
But...if my comment is extremely witty or funny I want to be acknowledged for being a genius. ::giggle::

I never mind getting replies from anyone, but I don't ever expect that people will reply to me.

I was going to say IDGAF, but then I got to thinking and Ethel always acknowledges my comments and I like that. So I'm going to say, yes, you should acknowledge the comments. But you know what? It's your blog. Do whatever you want.

:-)